Fraîchement remercié par ses employeurs, un col blanc prépare son départ en ruminant sa rancœur. Au même moment, un mystérieux virus éclate, transformant chacun des membres de la firme en infecté assoiffé de sang...

The International Space Station is now a prison - the ultimate black site. No one's getting out. And no one knows it's there. But when the imprisoned terrorists take over the Station and turn it into a missile aimed at Moscow, only a shuttle pilot and a rookie doctor can stop them. Their task is complicated by a rogue CIA agent (Scott Adkins) who has his own plans for the station and the terrorists within.