Five stories blend with love, sex, the emptiness of being unloved, passion and desire: Carlos and Susana go to some uncle´s apartment to make love. Meanwhile, Benito, an 80-year-old, performs a serenade to his wife. His neighbor Adela is told that her mother has Alzheimer and that she will be relocated since the Buenos Aires building she lives in will be demolished. Amado catches his son Carlos stealing his money. Gabriel asks Martha´s parents for her hand in marriage but they condition them to get married at their favorite church. And Patricia, 40, a creative agent, sexually abuses Joel, who directs a beer commercial.

L'histoire d'amour et de haine entre Rudo et Cursi, deux frères issus d'une famille rurale mexicaine et qui veulent devenir riches et célèbres coûte que coûte. Ils vont finir par y arriver, mais à quel prix ?